Pharmacology is a branch of biomedical science, encompassing clinical pharmacology, that is concerned with the effects of drugs/pharmaceuticals and other xenobiotics on living systems, as well as their development and chemical properties.
Related Subjects
- Clinical pharmacology
- Pharmacodynamics
- Pharmacogenetics
- Pharmacokinetics
- Receptor pharmacology
Latest Research and Reviews
Epigenetic mechanisms of rapid-acting antidepressants
- Antonio Inserra
- Antonella Campanale
- Tiziana Rubino
Reviews Open Access 04 Sept 2024 Translational Psychiatry
Volume: 14, P: 359
Pharmacological and non-pharmacological predictors of the LSD experience in healthy participants
- Patrick Vizeli
- Erich Studerus
- Matthias E. Liechti
Research Open Access 04 Sept 2024 Translational Psychiatry
Volume: 14, P: 357
GLP-1 receptor agonist exenatide uncouples food intake from hedonic and anticipatory regulation in non-human primates: insights from an operant meal schedule paradigm
- Balázs Knakker
- Judit Inkeller
- István Hernádi
Research Open Access 04 Sept 2024 Neuropsychopharmacology
Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data
Here the authors use drug susceptibility data from Plasmodium falciparum field isolates in a pharmacometric model to evaluate cabamiquine and pyronaridine efficacy, both individually and in combination. The combined treatment shows over 90% parasite reduction in most simulated cases, providing valuable guidance for clinical dose selection in real-world settings.
- Mohamed Maiga
- Laurent Dembele
- Claudia Demarta-Gatsi
Research Open Access 03 Sept 2024 Nature Communications
Volume: 15, P: 7659
Structural basis for CCR6 modulation by allosteric antagonists
Small molecule antagonists of CCR6 are potential drugs for autoimmune disorders. Here the authors present inactive structures of CCR6 bound by different allosteric antagonists from two series simultaneously, offering multiple approaches to inhibit CCR6.
- David Jonathan Wasilko
- Brian S. Gerstenberger
- Huixian Wu
Research Open Access 31 Aug 2024 Nature Communications
Volume: 15, P: 7574
Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis
- Ingrid R. S. B. Dias
- Rafaela G. A. Costa
- Daniel P. Bezerra
